I wrote an experiment implementation of writing PNG to the clipboard (aka copying from Firefox) and I actually have issues finding an app where this produces any kind of noticeable difference. Sadly I don't own Microsoft Office. I haven't noticed anything in Paint 3D or Paint.net. What is sort of interesting is that many apps seems to prefer CF_HDROP over CF_DIBV5 or "PNG". Chrome doesn't offer that format when copying images. This is also the cause of bug 1765665 and various duplicates.
Bug 1717306 Comment 6 Edit History
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I wrote an experimental implementation of writing PNG to the clipboard (aka copying from Firefox) and I actually have issues finding an app where this produces any kind of noticeable difference. Sadly I don't own Microsoft Office. I haven't noticed anything in Paint 3D or Paint.net. What is sort of interesting is that many apps seems to prefer CF_HDROP over CF_DIBV5 or "PNG". Chrome doesn't offer that format when copying images. This is also the cause of bug 1765665 and various duplicates.