I see you have "Sophos Intercept X" installed. Sophos seems have caused performance issues to some users. Could you perhaps try to disable it? (when disable, I'd use still Windows Defender, or whatever the builtin anti-virus tool is called). If that doesn't help, could you create a new performance profile, but enable first all the threads in the profiler's settings "Bypass selections above and record all registered threads".
Bug 1835223 Comment 10 Edit History
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I see you have "Sophos Intercept X" installed. Sophos seems have caused performance issues to some of its users. Could you perhaps try to disable it? (when disable, I'd use still Windows Defender, or whatever the builtin anti-virus tool is called). If that doesn't help, could you create a new performance profile, but enable first all the threads in the profiler's settings "Bypass selections above and record all registered threads".